When programmatically creating or updating a Collection Entry, you can lean on the Collection’s Blueprint to help you validate the fields values:

 1<?php
 2 
 3use Statamic\Facades\Blueprint;
 4use Statamic\Facades\Entry;
 5 
 6$data = [
 7  'slug' => 'some-title',
 8  'title' => 'Some title',
 9  // more data
10];
11 
12// validate the data
13$validated_data = Blueprint::setDirectory('resources/blueprints/collections/my_collection')
14      ->find('my_collection')
15      ->fields()
16      ->addValues($data)
17      ->validator()->validate();
18 
19// create & save the entry with the validated data
20$entry = Entry::make()
21  ->collection('my_collection')
22  ->slug(data_get($validated_data, 'slug'))
23  ->published()
24  ->data($validated_data);
25 
26$entry->save();